Pagine dedicate alla Neurologia per l'aggiornamento dei Colleghi e per informazioni sulle nuove terapie e descrizioni di patologie rivolte in modo comprensibile ai pazienti

                                                                                          Dott. Carlo Sebastiano Tadeo
                                                                                                Specialista Neurologia

Risonanza e diagnosi precoce dell' Alzheimer

 

                           Iscrivetevi alle Newsletter                   

                                             Newsletter  

 

 

 Novità dai principali congressi e pubblicazioni scientifiche 

Journals neurology

Per prenotare una visita neurologica

Servizio Traduzione

Medline

Congressi e convegni

Malattie neurologiche

Ictus
Sclerosi Multipla
Alzheimer
Parkinson
Neuropatie ereditarie
Cefalee

 

 

Pubblicità e links utili

 

We subscribe to the HONcode principles of the HON Foundation. Click to verify. We subscribe to the HONcode principles. Verify here.

 

 

www.ilneurologo.com - Candidato al Premio Web Italia 2003

Hippocampal Volume Loss Measured In Cognitively Impaired Elders



06/09/2000
By Anne MacLennan


Hippocampal atrophy rates match both baseline cognitive status and change in that status over time in elders on the continuum from normal cognition through to probable Alzheimer's, a study has found.

In older people, the cognitive continuum can be conceptually divided into those who are functioning normally (controls), those with mild cognitive impairment (MCI) and those with probable Alzheimer's disease (AD).

This study tested the hypothesis that the annualized rates of hippocampal atrophy differ as a function of both baseline status and change in clinical group membership (i.e. control, MCI or AD).

Authors identified 129 subjects from the Mayo Clinic AD Research Center/AD Patient Registry. All met criteria for normal controls, MCI or probable AD, both at entry and at time of a clinical follow-up evaluation about three years later.

At both initial assessment and follow-up, each subject underwent a magnetic resonance imaging (MRI) examination of the head and the annualized percentage change in hippocampal volume was computed. People classified as controls or MCI at baseline could either remain cognitively stable or decline to a lower functioning group.

For each of the initial three clinical groups, annualized rates of hippocampal volume loss decreased progressively in the following order: AD>MC>control.

In the control and MCI groups, those who declined clinically had a significantly greater rate of volume loss than did those who remained stable.

Mean annualized rates of atrophy by follow-up clinical group were as follows: control-stable 1.73 per cent, control-decliner 2.81 per cent, MCI-stable 2.55 per cent, MCI-decliner 3.69 per cent, AD 3.5 per cent.

 

Per ulteriori informazioni, contattare:

Il Neurologo con voi
Via Copernico 59/a Milano 20125
Tel: 03332699103
Posta elettronica: tadeo@ilneurologo.com

            

Spazio pubblicitario libero

 

Inviare a tadeo@ilneurologo.com un messaggio di posta elettronica contenente domande o commenti su questo sito Web.
Aggiornato il: 18 November 2001